Manchester United will host Arsenal at Old Trafford in a blockbuster fixture on the opening weekend of the 2025/26 Premier League, which officially begins with a Friday-night fixture as champions Liverpool start their title defence at home to AFC Bournemouth.
After finishing runners-up the past three seasons, Arsenal will look to go one better this campaign and will start their quest to end a 22-year title drought on Sunday 17 August with a trip to Old Trafford, where they have won only twice in the league in the last 18 years.
Arsenal will face a Man Utd team who struggled last season, finishing 15th, but head coach Ruben Amorim has already boosted his squad with the signing of forward Matheus Cunha from Wolverhampton Wanderers. United are also the club with the best record in the Premier League on opening weekends.
Arsenal have yet to announce a signing but Mikel Arteta has called the summer window a big one for the club. The Gunners face a tricky start, with all three of their opponents after a Matchweek 2 home match with Leeds United finishing in the top seven last season.
2025/26 Matchweek 1 fixtures (all times BST)
Friday 15 August 2025
20:00 Liverpool v AFC Bournemouth
Saturday 16 August
12:30 Aston Villa v Newcastle United
15:00 Brighton & Hove Albion v Fulham
15:00 Nottingham Forest v Brentford
15:00 Sunderland v West Ham United
15:00 Tottenham Hotspur v Burnley
17:30 Wolverhampton Wanderers v Manchester City
Sunday 17 August
14:00 Chelsea v Crystal Palace
16:30 Manchester United v Arsenal
Monday 18 August
20:00 Leeds United v Everton
