The Scotland captain missed the Champions League victory against Porto in midweek through suspension.
The fit-again Joe Gomez is available, having been named on the bench in midweek, and Adam Lallana is set to be in contention despite a recent injury.
Jurgen Klopp’s men need a win to keep their Premier League title hopes alive, particularly with Manchester City still holding a game in hand ahead of the run-in.
The Reds have an almost fully-fit squad to select from, leaving the German manager with a headache ahead of kick-off.
Gomez has returned to training and is in contention to feature against the Blues, although Dejan Lovren impressed as a replacement for Joel Matip at centre-back in midweek.
Meanwhile, Naby Keita also shone in the 2-0 victory but could drop out in favour of Georginio Wijnaldum after the Dutchman was rested last time out.
Fabinho should anchor the midfield and Jordan Henderson is likely to also retain his spot for the crunch clash.
Therefore, James Milner may have to be content with a place on the bench after deputising for Robertson at left-back against Porto.
Fellow midfielder Alex Oxlade-Chamberlain is another option for Klopp although the 25-year-old is still short of match action and is unlikely to be risked.
The usual front three of Mohamed Salah, Sadio Mane and Roberto Firmino will start once more with Divock Origi and Daniel Sturridge options off the bench.
Speaking ahead of the the game, Klopp said: “I feel the positive energy. It’s a massive change from surprise we are up there to getting used to it and getting more confident.
“The five or 10 seconds after the Tottenham equaliser [at Anfield two weeks ago] was the best reaction in the stadium.
“We really feel as one with the supporters as a whole group. You don’t walk alone, you’re never alone in these situations.
“We are trying to keep this dream alive and at the moment it’s all good.”
Liverpool predicted starting XI vs Chelsea: Allison; Alexander-Arnold, Lovren, Van Dijk, Robertson; Fabinho, Henderson, Wijnaldum; Salah, Mane, Firmino